TLK2 Antikörper (AA 141-171)

Produktnummer ABIN3029189

Der Kaninchen Polyklonal Anti-TLK2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, TLK2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für TLK2 Antikörper (AA 141-171) (ABIN3029189)

Target: TLK2 (Tousled-Like Kinase 2 (TLK2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TLK2 Antikörper

Bindungsspezifität: AA 141-171

Aufreinigung: Purified

Immunogen: A portion of amino acids 141-171 from the human protein was used as the immunogen for this TLK2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the TLK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TLK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TLK2

Target: TLK2 (Tousled-Like Kinase 2 (TLK2))

Andere Bezeichnung: TLK2

Hintergrund: TLK2, a member of the Ser/Thr protein kinase family, is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. The TLK2 enzyme is cell-cycle regulated, with maximal activity in S-phase. It is inactivated by phosphorylation at Ser-750, potentially by CHK1. TLK2 heterodimerizes with TLK1. This nuclear protein is widely expressed, with presence in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle tissues, and in several adult cell lines.

UniProt: Q86UE8