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TLK2 Antikörper (AA 141-171)

This anti-TLK2 antibody (ABIN3029189) is a Rabbit Polyclonal antibody detecting TLK2 in WB, ELISA. Suitable for Human, Mouse.
Produktnummer ABIN3029189

Kurzübersicht für TLK2 Antikörper (AA 141-171) (ABIN3029189)

Target

Alle TLK2 Antikörper anzeigen
TLK2 (Tousled-Like Kinase 2 (TLK2))

Reaktivität

  • 54
  • 22
  • 16
  • 5
  • 5
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus

Wirt

  • 51
  • 3
Kaninchen

Klonalität

  • 51
  • 3
Polyklonal

Konjugat

  • 24
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TLK2 Antikörper ist unkonjugiert

Applikation

  • 42
  • 20
  • 13
  • 13
  • 6
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 141-171

    Aufreinigung

    Purified

    Immunogen

    A portion of amino acids 141-171 from the human protein was used as the immunogen for this TLK2 antibody.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Titration of the TLK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot the TLK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    TLK2 (Tousled-Like Kinase 2 (TLK2))

    Andere Bezeichnung

    TLK2

    Hintergrund

    TLK2, a member of the Ser/Thr protein kinase family, is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. The TLK2 enzyme is cell-cycle regulated, with maximal activity in S-phase. It is inactivated by phosphorylation at Ser-750, potentially by CHK1. TLK2 heterodimerizes with TLK1. This nuclear protein is widely expressed, with presence in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle tissues, and in several adult cell lines.

    UniProt

    Q86UE8
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