SUZ12 Antikörper (AA 559-588)

Produktnummer ABIN3029056

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SUZ12 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für SUZ12 Antikörper (AA 559-588) (ABIN3029056)

Target: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUZ12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SUZ12 Antikörper

Bindungsspezifität: AA 559-588

Verwendungszweck: SUZ12 Antibody / Suppressor of zeste 12 protein homolog

Kreuzreaktivität (Details): Expected species reactivity: Mouse

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 559-588 from the human protein was used as the immunogen for this SUZ12 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the SUZ12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SUZ12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu SUZ12

Target: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Andere Bezeichnung: SUZ12

Hintergrund: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

UniProt: Q15022