SPR Antikörper (AA 231-260)
Kurzübersicht für SPR Antikörper (AA 231-260) (ABIN3029000)
Target
Alle SPR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 231-260
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Verwendungszweck
- SPR Antibody / Sepiapterin reductase
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 231-260 from the human protein was used as the immunogen for this SPR antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the SPR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the SPR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SPR (Sepiapterin Reductase (SPR))
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Andere Bezeichnung
- SPR
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Hintergrund
- SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
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UniProt
- P35270
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Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
Target
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