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SOX2 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-SOX2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, SOX2 in Proben von Human zu detektieren.
Produktnummer ABIN3032729

Kurzübersicht für SOX2 Antikörper (N-Term) (ABIN3032729)

Target

Alle SOX2 Antikörper anzeigen
SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reaktivität

  • 246
  • 140
  • 73
  • 21
  • 13
  • 11
  • 10
  • 10
  • 8
  • 8
  • 7
  • 7
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 185
  • 70
  • 2
Kaninchen

Klonalität

  • 162
  • 95
Polyklonal

Konjugat

  • 122
  • 14
  • 14
  • 10
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Dieser SOX2 Antikörper ist unkonjugiert

Applikation

  • 165
  • 98
  • 93
  • 49
  • 45
  • 42
  • 40
  • 40
  • 30
  • 24
  • 22
  • 21
  • 16
  • 12
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 60
    • 16
    • 15
    • 15
    • 15
    • 10
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Aufreinigung

    Antigen affinity purified

    Immunogen

    This SOX2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 30-63 amino acids from the N-terminal region of human SOX2.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Titration of the SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot the SOX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

    Andere Bezeichnung

    SOX2

    Hintergrund

    Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

    UniProt

    P48431

    Pathways

    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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