SOX17 Antikörper (C-Term)
Kurzübersicht für SOX17 Antikörper (C-Term) (ABIN3032723)
Target
Alle SOX17 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 376-409, C-Term
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Verwendungszweck
- Sox17 Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- This Sox17 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of mouse Sox17.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the Sox17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Sox17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))
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Andere Bezeichnung
- Sox17
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Hintergrund
- Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.
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UniProt
- Q61473
Target
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