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SIRT5 Antikörper (AA 263-292)

SIRT5 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032595
  • Target Alle SIRT5 Antikörper anzeigen
    SIRT5 (Sirtuin 5 (SIRT5))
    Bindungsspezifität
    • 16
    • 10
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 263-292
    Reaktivität
    • 82
    • 45
    • 30
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Human
    Wirt
    • 81
    • 6
    • 2
    • 2
    Kaninchen
    Klonalität
    • 77
    • 14
    Polyklonal
    Konjugat
    • 39
    • 16
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SIRT5 Antikörper ist unkonjugiert
    Applikation
    • 75
    • 38
    • 27
    • 15
    • 13
    • 12
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 263-292 from the human protein was used as the immunogen for this SIRT5 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SIRT5 Primärantikörper
  • Applikationshinweise
    Titration of the SIRT5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the SIRT5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    SIRT5 (Sirtuin 5 (SIRT5))
    Andere Bezeichnung
    SIRT5 (SIRT5 Produkte)
    Synonyme
    SIR2L5 antikoerper, 0610012J09Rik antikoerper, 1500032M05Rik antikoerper, AV001953 antikoerper, zgc:92288 antikoerper, sirt5-a antikoerper, SIRT5 antikoerper, sir2l5 antikoerper, sirtuin 5 antikoerper, sirtuin 5 L homeolog antikoerper, SIRT5 antikoerper, Sirt5 antikoerper, sirt5 antikoerper, sirt5.L antikoerper, CC1G_00083 antikoerper
    Hintergrund
    SIRT5 is an NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinylation and activation of HMGCS2 (By similarity). Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX. [UniProt]
    UniProt
    Q9NXA8
    Pathways
    SARS-CoV-2 Protein Interaktom
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