PROX1 Antikörper (AA 492-520)
Kurzübersicht für PROX1 Antikörper (AA 492-520) (ABIN3032345)
Target
Alle PROX1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 492-520
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Verwendungszweck
- PROX1 Antibody / Prospero homeobox 1
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 492-520 from the human protein was used as the immunogen for this PROX1 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the PROX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the PROX1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PROX1 (Prospero Homeobox 1 (PROX1))
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Andere Bezeichnung
- PROX1
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Hintergrund
- Prospero homeobox protein 1 is a transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3. [UniProt]
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UniProt
- Q92786
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Pathways
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
Target
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