SOX2 Antikörper (pSer249)
Kurzübersicht für SOX2 Antikörper (pSer249) (ABIN3032734)
Target
Alle SOX2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer249
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse
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Aufreinigung
- Antigen affinity purified
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Immunogen
- This phos-SOX2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS249 of human SOX2.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the phos-SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the phos-SOX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Andere Bezeichnung
- SOX2
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Hintergrund
- This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
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UniProt
- P48431
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Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
Target
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