OSCAR
Reaktivität: Human
WB, IHC, IP, ICC
Wirt: Maus
Monoclonal
C4
unconjugated
Applikationshinweise
Titration of the OSCAR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the OSCAR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
OSCAR
(Osteoclast Associated Receptor (OSCAR))
Andere Bezeichnung
OSCAR
Hintergrund
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.