NUP50 Antikörper (AA 432-461)

Produktnummer ABIN3032078

Der Kaninchen Polyklonal anti-NUP50 Antikörper wird verwendet zum Nachweis von NUP50 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für NUP50 Antikörper (AA 432-461) (ABIN3032078)

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP50 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NUP50 Antikörper

Bindungsspezifität: AA 432-461

Verwendungszweck: NUP50 Antibody

Kreuzreaktivität (Details): Expected species reactivity: Rat

Aufreinigung: Purified

Immunogen: A portion of amino acids 432-461 from the human protein was used as the immunogen for this NUP50 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the NUP50 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the NUP50 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu NUP50

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Andere Bezeichnung: NUP50

Hintergrund: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.

UniProt: Q9UKX7

Pathways: Tube Formation