MCM8 Antikörper (AA 322-350)

Produktnummer ABIN3031814

Produktdetails anti-MCM8 Antikörper

Target: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Bindungsspezifität: AA 322-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 322-350 from the human protein was used as the immunogen for this MCM8 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the MCM8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MCM8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu MCM8

Target: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Andere Bezeichnung: MCM8 (MCM8 Produkte)

Synonyme: C20orf154 antikoerper, dJ967N21.5 antikoerper, 5730432L01Rik antikoerper, minichromosome maintenance 8 homologous recombination repair factor antikoerper, minichromosome maintenance 8 homologous recombination repair factor L homeolog antikoerper, MCM8 antikoerper, Mcm8 antikoerper, mcm8.L antikoerper

Hintergrund: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.

UniProt: Q9UJA3

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA