LOX Antikörper (AA 234-260)
Kurzübersicht für LOX Antikörper (AA 234-260) (ABIN3031667)
Target
Alle LOX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 234-260
-
Verwendungszweck
- LOX Antibody / Lysyl Oxidase
-
Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat, Pig
-
Aufreinigung
- Purified
-
Immunogen
- A portion of amino acids 234-260 from the human protein was used as the immunogen for this LOX antibody.
-
Isotyp
- IgG2b
-
-
-
-
Applikationshinweise
- Titration of the LOX antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the LOX antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- LOX (Lysyl Oxidase (LOX))
-
Andere Bezeichnung
- LOX
-
Hintergrund
- The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
-
UniProt
- P28300
-
Pathways
- SARS-CoV-2 Protein Interaktom
Target
-