KEAP1 Antikörper (AA 422-449)

Produktnummer ABIN3031535

Produktdetails anti-KEAP1 Antikörper

Target: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Bindungsspezifität: AA 422-449

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KEAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): Expected species reactivity: Pig

Aufreinigung: Purified

Immunogen: A portion of amino acids 422-449 from the human protein was used as the immunogen for this KEAP1 antibody.

Klon: 297CT6-1-6

Isotyp: IgM kappa

Anwendungsinformationen

Applikationshinweise: Titration of the KEAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the KEAP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu KEAP1

Target: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Andere Bezeichnung: KEAP1 (KEAP1 Produkte)

Hintergrund: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

UniProt: Q14145

Pathways: Maintenance of Protein Location