IRF8 Antikörper (AA 384-409)

Produktnummer ABIN3031424

Der Kaninchen Polyklonal Anti-IRF8-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, IRF8 in Proben von Human zu detektieren.

Kurzübersicht für IRF8 Antikörper (AA 384-409) (ABIN3031424)

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-IRF8 Antikörper

Bindungsspezifität: AA 384-409

Aufreinigung: Purified

Immunogen: A portion of amino acids 384-409 from the human protein was used as the immunogen for this IRF8 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the IRF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the IRF8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu IRF8

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Andere Bezeichnung: IRF8

Hintergrund: Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin