IQGAP1
Reaktivität: Human
WB, IHC, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Titration of the IQGAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the IQGAP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
IQGAP1
(IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))
Andere Bezeichnung
IQGAP1
Hintergrund
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.