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Integrin beta 7 Antikörper (AA 737-765)

Der Rabbit Polyclonal Anti-Integrin beta 7-Antikörper wurde für WB, ELISA validiert. Er ist geeignet, Integrin beta 7 in Proben von Human zu detektieren.
Produktnummer ABIN3031382

Kurzübersicht für Integrin beta 7 Antikörper (AA 737-765) (ABIN3031382)

Target

Alle Integrin beta 7 (ITGB7) Antikörper anzeigen
Integrin beta 7 (ITGB7)

Reaktivität

  • 77
  • 31
  • 1
  • 1
  • 1
Human

Wirt

  • 50
  • 20
  • 7
  • 4
  • 1
Kaninchen

Klonalität

  • 51
  • 29
  • 2
Polyklonal

Konjugat

  • 36
  • 8
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Integrin beta 7 Antikörper ist unkonjugiert

Applikation

  • 40
  • 28
  • 21
  • 13
  • 13
  • 9
  • 8
  • 8
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 8
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 737-765

    Aufreinigung

    Antigen affinity purified

    Immunogen

    A portion of amino acids 737-765 from the human protein was used as the immunogen for this Integrin beta 7 antibody.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Titration of the Integrin beta 7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot the Integrin beta 7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    Integrin beta 7 (ITGB7)

    Andere Bezeichnung

    Integrin beta 7

    Hintergrund

    Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.

    UniProt

    P26010

    Pathways

    Integrin Complex
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