GAK Antikörper (AA 15-45)

Produktnummer ABIN3030600

Der Kaninchen Polyklonal anti-GAK Antikörper (ABIN3030600) detektiert spezifisch GAK in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für GAK Antikörper (AA 15-45) (ABIN3030600)

Target: GAK (Cyclin G Associated Kinase (GAK))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-GAK Antikörper

Bindungsspezifität: AA 15-45

Kreuzreaktivität (Details): Expected species reactivity: Rat

Aufreinigung: Purified

Immunogen: A portion of amino acids 15-45 from the human protein was used as the immunogen for this GAK antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the GAK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the GAK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu GAK

Target: GAK (Cyclin G Associated Kinase (GAK))

Andere Bezeichnung: GAK

Hintergrund: GAK, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5. It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK localizes to the perinuclear area and to the trans-Golgi network. It is also observed on the plasma membrane, probably at focals adhesions. Expression is ubiquitous, wiht highest levels in testis. The protein contains 1 J domain and 1 tensin domain.

UniProt: Q6P490