FKBP1A Antikörper (AA 43-74)

Produktnummer ABIN3030968

Der Kaninchen Polyklonal Anti-FKBP1A-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, FKBP1A in Proben von Human zu detektieren.

Kurzübersicht für FKBP1A Antikörper (AA 43-74) (ABIN3030968)

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-FKBP1A Antikörper

Bindungsspezifität: AA 43-74

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rat, Bovine, Rabbit

Aufreinigung: Purified

Immunogen: A portion of amino acids 43-74 from the human protein was used as the immunogen for this FKBP12 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the FKBP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the FKBP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu FKBP1A

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Andere Bezeichnung: FKBP12

Hintergrund: FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process