Fission 1 Antikörper (N-Term)

Produktnummer ABIN3030967

Produktdetails anti-Fission 1 Antikörper

Target: Fission 1 (FIS1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fission 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: This FIS1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 6-40 amino acids from the N-terminal region of human FIS1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the FIS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the FIS1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Fission 1

Target: Fission 1 (FIS1)

Andere Bezeichnung: FIS1 (FIS1 Produkte)

Synonyme: TTC11 antikoerper, 2010003O14Rik antikoerper, Ttc11 antikoerper, fission, mitochondrial 1 antikoerper, FIS1 antikoerper, Fis1 antikoerper

Hintergrund: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin- related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.

UniProt: Q9Y3D6

Pathways: Positive Regulation of Endopeptidase Activity