Dnmt2 Antikörper (AA 346-375)

Produktnummer ABIN3029268

Produktdetails anti-Dnmt2 Antikörper

Target: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Bindungsspezifität: AA 346-375

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dnmt2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Purified

Immunogen: A portion of amino acids 346-375 from the human protein was used as the immunogen for this Dnmt2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Dnmt2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Dnmt2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Dnmt2

Target: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Andere Bezeichnung: Dnmt2 (TRDMT1 Produkte)

Synonyme: MGC89267 antikoerper, DMNT2 antikoerper, DNMT2 antikoerper, MHSAIIP antikoerper, PUMET antikoerper, RNMT1 antikoerper, Dnmt2 antikoerper, Rnmt2 antikoerper, dnmt2 antikoerper, tRNA aspartic acid methyltransferase 1 antikoerper, tRNA aspartic acid methyltransferase 1 L homeolog antikoerper, trdmt1 antikoerper, TRDMT1 antikoerper, Trdmt1 antikoerper, trdmt1.L antikoerper

Hintergrund: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: O14717