Dnmt2 Antikörper (AA 346-375)
Kurzübersicht für Dnmt2 Antikörper (AA 346-375) (ABIN3029268)
Target
Alle Dnmt2 (TRDMT1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 346-375
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Verwendungszweck
- Dnmt2 Antibody
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 346-375 from the human protein was used as the immunogen for this Dnmt2 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the Dnmt2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Dnmt2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
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Andere Bezeichnung
- Dnmt2
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Hintergrund
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- O14717
Target
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