Dynamin 1-Like Antikörper (C-Term)

Produktnummer ABIN3030780

Produktdetails anti-Dynamin 1-Like Antikörper

Target: Dynamin 1-Like (DNM1L)

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamin 1-Like Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: This DNM1L antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 513-547 amino acids from the C-terminal region of human DRP1/DNM1L.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the DNM1L antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:8000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the DNM1L antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Andere Bezeichnung: DNM1L (DNM1L Produkte)

Synonyme: DLP1 antikoerper, DRP1 antikoerper, DVLP antikoerper, DYMPLE antikoerper, EMPF antikoerper, HDYNIV antikoerper, 6330417M19Rik antikoerper, AI450666 antikoerper, Dlp1 antikoerper, Dnmlp1 antikoerper, Drp1 antikoerper, python antikoerper, Dnml1 antikoerper, dnm1l antikoerper, MGC53850 antikoerper, zgc:66163 antikoerper, DNM1L antikoerper, 18.m06247 antikoerper, CG3210 antikoerper, DRP antikoerper, Dmel\CG3210 antikoerper, Dnm1/Drp1 antikoerper, Drp antikoerper, Drp-1 antikoerper, drp-1 antikoerper, drp1 antikoerper, frat antikoerper, l(2)22Fc antikoerper, l(2)22Fd antikoerper, l(2)ND2 antikoerper, l(2)ND3 antikoerper, dynamin 1 like antikoerper, dynamin 1-like antikoerper, dynamin 1-like L homeolog antikoerper, dynamin-1-like antikoerper, dynamin-1-like protein antikoerper, dynamin-like protein antikoerper, Dynamin related protein 1 antikoerper, DNM1L antikoerper, Dnm1l antikoerper, dnm1l.L antikoerper, dnm1l antikoerper, LOC100369408 antikoerper, LOC411472 antikoerper, dyn1 antikoerper, cgd1_580 antikoerper, EHI_052740 antikoerper, PVX_092875 antikoerper, BBOV_II002980 antikoerper, Drp1 antikoerper

Hintergrund: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis, this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles, the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. [UniProt]

UniProt: O00429