CEBPA Antikörper (AA 304-330)

Produktnummer ABIN3030343

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CEBPA in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für CEBPA Antikörper (AA 304-330) (ABIN3030343)

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEBPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-CEBPA Antikörper

Bindungsspezifität: AA 304-330

Kreuzreaktivität (Details): Expected species reactivity: Rat, Bovine

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 304-330 from the human protein was used as the immunogen for this CEBPA antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the CEBPA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CEBPA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CEBPA

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Andere Bezeichnung: CEBPA

Hintergrund: CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. This protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

UniProt: P49715

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation