Der Kaninchen Polyklonal anti-CD68 Antikörper (ABIN3030411) detektiert spezifisch CD68 in WB und ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
CD68
Reaktivität: Human
FACS
Wirt: Maus
Monoclonal
Y1-82A
PE
Applikationshinweise
Titration of the CD68 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS pH 7.4 with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the CD68 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
CD68
(CD68 Molecule (CD68))
Andere Bezeichnung
CD68
Hintergrund
This gene encodes a 40~110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.