CD43 Antikörper (AA 230-257)

Produktnummer ABIN3032562

Dieses Anti-CD43-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD43 in WB und ELISA. Geeignet für Human.

Kurzübersicht für CD43 Antikörper (AA 230-257) (ABIN3032562)

Target: CD43 (SPN) (Sialophorin (SPN))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD43 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 423CT7-9-2

Produktdetails anti-CD43 Antikörper

Bindungsspezifität: AA 230-257

Aufreinigung: Purified

Immunogen: A portion of amino acids 230-257 from the human protein was used as the immunogen for this CD43 antibody.

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Titration of the CD43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CD43 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CD43

Target: CD43 (SPN) (Sialophorin (SPN))

Andere Bezeichnung: CD43

Hintergrund: One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity) [UniProt]

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity