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CD163 Antikörper (AA 245-274)

CD163 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3030360
  • Target Alle CD163 Antikörper anzeigen
    CD163
    Bindungsspezifität
    • 16
    • 16
    • 15
    • 11
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 245-274
    Reaktivität
    • 136
    • 50
    • 30
    • 29
    • 20
    • 5
    • 4
    • 1
    Human
    Wirt
    • 108
    • 52
    • 1
    Kaninchen
    Klonalität
    • 92
    • 68
    • 1
    Polyklonal
    Konjugat
    • 55
    • 19
    • 13
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD163 Antikörper ist unkonjugiert
    Applikation
    • 111
    • 78
    • 50
    • 38
    • 27
    • 26
    • 26
    • 24
    • 22
    • 20
    • 15
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 245-274 from the human protein was used as the immunogen for this CD163 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CD163 Primärantikörper
  • Applikationshinweise
    Titration of the CD163 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the CD163 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    CD163
    Andere Bezeichnung
    CD163 (CD163 Produkte)
    Synonyme
    DMBT1 antikoerper, CD163 antikoerper, CD163v2 antikoerper, CD163v3 antikoerper, M130 antikoerper, MM130 antikoerper, deleted in malignant brain tumors 1 protein-like antikoerper, CD163 molecule antikoerper, CD163 antigen antikoerper, LOC426820 antikoerper, CD163 antikoerper, Cd163 antikoerper
    Hintergrund
    CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. It also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.
    UniProt
    Q86VB7
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