CCR3 Antikörper (AA 291-318)
Kurzübersicht für CCR3 Antikörper (AA 291-318) (ABIN3030491)
Target
Alle CCR3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 291-318
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Verwendungszweck
- CCR3 Antibody
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Kreuzreaktivität (Details)
- Expected species reactivity: Primate
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 291-318 from the human protein was used as the immunogen for this CCR3 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the CCR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the CCR3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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Andere Bezeichnung
- CCR3
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Hintergrund
- CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
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UniProt
- P51677
Target
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