BACE1 Antikörper (AA 476-501)
Kurzübersicht für BACE1 Antikörper (AA 476-501) (ABIN3030158)
Target
Alle BACE1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 476-501
-
Kreuzreaktivität (Details)
- Expected species reactivity: Rat, Bovine
-
Aufreinigung
- Purified
-
Immunogen
- A portion of amino acids 476-501 from the human protein was used as the immunogen for this BACE antibody.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- Titration of the BACE antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the BACE antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- BACE1 (Beta-secretase 1 (BACE1))
-
Andere Bezeichnung
- BACE
-
Hintergrund
- Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
-
UniProt
- P56817
Target
-