SOX2 Antikörper (AA 6-39)

Produktnummer ABIN3032725

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SOX2 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für SOX2 Antikörper (AA 6-39) (ABIN3032725)

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SOX2 Antikörper

Bindungsspezifität: AA 6-39

Aufreinigung: Antigen affinity purified

Immunogen: This anti-SOX-2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 6~39 amino acids from the N-terminal region of mouse Sox2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the anti-SOX-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the anti-SOX-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu SOX2

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Andere Bezeichnung: SOX-2

Hintergrund: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

UniProt: P48432

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis