CXCR4 Antikörper (AA 50-79)

Produktnummer ABIN3030512

Der Kaninchen Polyklonal anti-CXCR4 Antikörper wird verwendet zum Nachweis von CXCR4 in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für CXCR4 Antikörper (AA 50-79) (ABIN3030512)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CXCR4 Antikörper

Bindungsspezifität: AA 50-79

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rat, Bovine, Pig, Primate

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 50-79 from the human protein was used as the immunogen for this anti-CXCR4 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the anti-CXCR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the anti-CXCR4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Andere Bezeichnung: CXCR4

Hintergrund: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events