ANGPTL4 Antikörper (AA 138-167)

Produktnummer ABIN3029955

Dieses Anti-ANGPTL4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ANGPTL4 in WB, IHC, ELISA und FACS. Geeignet für Human und Maus.

Kurzübersicht für ANGPTL4 Antikörper (AA 138-167) (ABIN3029955)

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGPTL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Produktdetails anti-ANGPTL4 Antikörper

Bindungsspezifität: AA 138-167

Aufreinigung: Purified

Immunogen: A portion of amino acids 138-167 from the human protein was used as the immunogen for this ANGPTL4 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the ANGPTL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ANGPTL4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Andere Bezeichnung: ANGPTL4

Hintergrund: ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This protein is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes.

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha