APP Antikörper (AA 736-770)
Kurzübersicht für APP Antikörper (AA 736-770) (ABIN3029926)
Target
Alle APP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 736-770
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Verwendungszweck
- Amyloid beta Antibody
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Pig, Primate, Rat
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 736-770 from the human protein was used as the immunogen for this Amyloid beta antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the Amyloid beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Amyloid beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- APP (Amyloid beta (A4) Precursor Protein (APP))
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Andere Bezeichnung
- Amyloid beta Precusor Protein (APP)
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Hintergrund
- APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Aβ, is the main component of amyloid plaques (extracellular deposits found in the brains of patients with Alzheimer's disease).[19] Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis (a muscle disease), while Aβ, can also form the aggregates that coat cerebral blood vessels in cerebral amyloid angiopathy. [Wiki]
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UniProt
- P05067
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Pathways
- Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
Target
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