Titration of the Amyloid beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Amyloid beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
APP
(Amyloid beta (A4) Precursor Protein (APP))
Andere Bezeichnung
Amyloid beta Precusor Protein (APP)
Hintergrund
APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Aβ, is the main component of amyloid plaques (extracellular deposits found in the brains of patients with Alzheimer's disease).[19] Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis (a muscle disease), while Aβ, can also form the aggregates that coat cerebral blood vessels in cerebral amyloid angiopathy. [Wiki]