SIRT6 Antikörper

Produktnummer ABIN4953432

Dieser Maus Monoklonal Antikörper detektiert spezifisch SIRT6 in WB, IP, ICC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Primate.

Kurzübersicht für SIRT6 Antikörper (ABIN4953432)

Target: SIRT6 (Sirtuin 6 (SIRT6))

Reaktivität: Human, Maus, Ratte, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SIRT6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: 6C9-D10-D3

Produktdetails anti-SIRT6 Antikörper

Aufreinigung: Protein G affinity

Immunogen: A human recombinant protein was used as the immunogen for this SIRT6 antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,ICC/IF: 1:100,Immunoprecipitation: suitable

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

Lagerung: -20 °C

Informationen zur Lagerung: Store the SIRT6 antibody at -20°C.

Details zu SIRT6

Target: SIRT6 (Sirtuin 6 (SIRT6))

Andere Bezeichnung: SIRT6

Hintergrund: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. [UniProt]

UniProt: Q8N6T7