SIRT6 Antikörper

Produktnummer ABIN4953432

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SIRT6 in WB, IP, ICC und IF. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte und Primate.

Kurzübersicht für SIRT6 Antikörper (ABIN4953432)

Target: SIRT6 (Sirtuin 6 (SIRT6))

Reaktivität: Human, Maus, Ratte, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SIRT6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: 6C9-D10-D3

Produktdetails anti-SIRT6 Antikörper

Aufreinigung: Protein G affinity

Immunogen: A human recombinant protein was used as the immunogen for this SIRT6 antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,ICC/IF: 1:100,Immunoprecipitation: suitable

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

Lagerung: -20 °C

Informationen zur Lagerung: Store the SIRT6 antibody at -20°C.

Details zu SIRT6

Target: SIRT6 (Sirtuin 6 (SIRT6))

Andere Bezeichnung: SIRT6

Hintergrund: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. [UniProt]

UniProt: Q8N6T7