KEAP1 Antikörper (AA 422-449)
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- Target Alle KEAP1 Antikörper anzeigen
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
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Bindungsspezifität
- AA 422-449
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KEAP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität (Details)
- Expected species reactivity: Pig
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 422-449 from the human protein was used as the immunogen for this KEAP1 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product KEAP1 Primärantikörper
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anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 325-624) antibody
KEAP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 1F10B6 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 Reaktivität: Human ELISA, IHC, FACS Wirt: Maus Monoclonal 7G4B10 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibodyKEAP1 Reaktivität: Human, Maus WB, IHC, IHC (p), FACS Wirt: Maus Monoclonal 1B4 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibodyKEAP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (C-Term) antibodyKEAP1 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 1-286) antibodyKEAP1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 65-160) antibodyKEAP1 Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 41-53) antibodyVerified KEAP1 Reaktivität: Human ELISA, IHC, IF Wirt: Ziege Polyclonal unconjugated
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- Applikationshinweise
- The stated application concentrations are suggested starting amounts. Titration of the KEAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at 4°C for up to one month. For long term, aliquot the KEAP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
- Andere Bezeichnung
- KEAP1 (KEAP1 Produkte)
- Hintergrund
- KEAP1 acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome [UniProt]
- UniProt
- Q14145
- Pathways
- Maintenance of Protein Location
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