BACE1 Antikörper (AA 38-70)
Kurzübersicht für BACE1 Antikörper (AA 38-70) (ABIN3030159)
Target
Alle BACE1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 38-70
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Kreuzreaktivität (Details)
- Expected species reactivity: Rat, Bovine
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 38-70 from the human protein was used as the immunogen for this BACE1 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- The stated application concentrations are suggested starting amounts. Titration of the BACE1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at 4°C for up to one month. For long term, aliquot the BACE1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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Andere Bezeichnung
- BACE1
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Hintergrund
- Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. [UniProt]
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UniProt
- P56817
Target
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