Der Kaninchen Polyklonal anti-SGCA Antikörper (ABIN4952537) detektiert spezifisch SGCA in WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
SGCA
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
Optimal dilution of the SGCA antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
-20 °C
Informationen zur Lagerung
After reconstitution, the SGCA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Alpha-sarcoglycan is a protein that in humans is encoded by the SGCA gene. This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.