Surfactant Protein A1 Antikörper

Produktnummer ABIN4952536

Der Kaninchen Polyklonal anti-Surfactant Protein A1 Antikörper wird verwendet zum Nachweis von Surfactant Protein A1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC (p), IF und IHC (fro).

Kurzübersicht für Surfactant Protein A1 Antikörper (ABIN4952536)

Target: Surfactant Protein A1 (SFTPA1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Surfactant Protein A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Surfactant Protein A1 Antikörper

Verwendungszweck: SFTPA1/2 Antibody

Sequenz: VNYTNWYRGE PAGRGKEQCV EMYTDGQWND RN

Aufreinigung: Antigen affinity

Immunogen: Amino acids VNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRN of human SFTPA1/2 were used as the immunogen for the SFTPA1/2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SFTPA1/2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SFTPA1/2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Surfactant Protein A1

Target: Surfactant Protein A1 (SFTPA1)

Andere Bezeichnung: SFTPA1/2

Hintergrund: SFTPA1/2 is also known as SP-A. SFTPA1 encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants. SFTPA2 is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication.

UniProt: Q8IWL1