TIMP2 Antikörper (N-Term)

Produktnummer ABIN4949918

Dieses Anti-TIMP2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TIMP2 in WB, IF und IHC (p). Geeignet für Human, Ratte und Maus.

Kurzübersicht für TIMP2 Antikörper (N-Term) (ABIN4949918)

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reaktivität: Human, Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TIMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: SPM356

Produktdetails anti-TIMP2 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Protein G affinity chromatography

Immunogen: An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TIMP2 antibody to be titered up or down for optimal performance.\. IHC (FFPE): 0.5-1 μg/mL for 30 min at RT,WB: 0.5-1 μg/mL,IF: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the TIMP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu TIMP2

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Andere Bezeichnung: TIMP2

Hintergrund: It recognizes a protein of 21  kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72  kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92  kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Pathways: cAMP Metabolic Process