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CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) Antikörper

Reaktivität: Human IHC (p), IF Wirt: Maus Monoclonal CFTR-1643 unconjugated
Produktnummer ABIN4949564
  • Target
    CFTR / Cystic Fibrosis Transmembrane Regulator
    Bindungsspezifität
    AA 258-385
    Reaktivität
    • 9
    • 4
    Human
    Wirt
    • 5
    • 4
    Maus
    Klonalität
    • 9
    Monoklonal
    Konjugat
    • 9
    Unkonjugiert
    Applikation
    • 9
    • 7
    • 4
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Aufreinigung
    Protein G affinity chromatography
    Immunogen
    A partial recombinant protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this CFTR antibody.
    Klon
    CFTR-1643
    Isotyp
    IgG2b
  • Applikationshinweise
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.\. IF: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target
    CFTR / Cystic Fibrosis Transmembrane Regulator
    Hintergrund
    Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]
    Gen-ID
    1080
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