CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) Antikörper

Produktnummer ABIN4949564

Der Maus Monoklonal anti-CFTR / Cystic Fibrosis Transmembrane Regulator Antikörper (Klon CFTR-1643) (ABIN4949564) detektiert spezifisch CFTR / Cystic Fibrosis Transmembrane Regulator in IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) Antikörper (ABIN4949564)

Target: CFTR / Cystic Fibrosis Transmembrane Regulator

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: CFTR-1643

Produktdetails

Bindungsspezifität: AA 258-385

Verwendungszweck: CFTR Antibody (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: A partial recombinant protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this CFTR antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the CFTR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Antigendetails

Target: CFTR / Cystic Fibrosis Transmembrane Regulator

Hintergrund: Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]

UniProt: P13569