CD81 Antikörper

Produktnummer ABIN4949542

Der Maus Monoklonal Anti-CD81-Antikörper wurde für FACS, WB, IF, Func und IHC (p) validiert. Er ist geeignet, CD81 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CD81 Antikörper (ABIN4949542)

Target: CD81

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD81 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1-3-3-22

Produktdetails anti-CD81 Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: A B-cell line derived from a Burkitt lymphoma was used as the immunogen for the CD81 antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CD81 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,WB: 0.5-1 μg/mL,Functional Studies: order BSA free formulation,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the CD81 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu CD81

Target: CD81

Andere Bezeichnung: CD81

Hintergrund: This mAb recognizes a protein of 26  kDa, identified as CD81 (Workshop VI, Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

Pathways: Inositol Metabolic Process, Hepatitis C