CD44v6 Antikörper

Produktnummer ABIN4949524

Der Maus Monoklonal Anti--Antikörper wurde für FACS, IF und IHC (p) validiert. Er ist geeignet, in Proben von Human zu detektieren.

Kurzübersicht für CD44v6 Antikörper (ABIN4949524)

Target: CD44v6

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: CD44v6-1246

Produktdetails

Aufreinigung: Protein G affinity chromatography

Immunogen: An amino acid sequence from the variant 6 domain of CD44 was used as the immunogen for the CD44v6 antibody.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Titering of the CD44v6 antibody may be required for optimal performance.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the CD44v6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Antigendetails

Target: CD44v6

Hintergrund: This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44. The CD44 Molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.