PTH Antikörper (N-Term)

Produktnummer ABIN4949381

Der Kaninchen Polyklonal anti-PTH Antikörper (ABIN4949381) detektiert spezifisch PTH in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PTH Antikörper (N-Term) (ABIN4949381)

Target: PTH (Parathyroid Hormone (PTH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTH Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Produktdetails anti-PTH Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PTH Antibody / N-Terminal (azide and preservative free)

Aufreinigung: Protein A affinity chromatography

Immunogen: A synthetic peptide from the N-terminal region of human Parathyroid hormone was used as the immunogen for the PTH antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PTH antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the PTH antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu PTH

Target: PTH (Parathyroid Hormone (PTH))

Andere Bezeichnung: PTH

Substanzklasse: Hormone

Hintergrund: PTH/Parathyroid hormone is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

UniProt: P01270

Pathways: cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process