CD1a Antikörper
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- Target Alle CD1a Antikörper anzeigen
- CD1a
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD1a Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Protein A affinity chromatography
- Immunogen
- Human CD1a protein was used as the immunogen for this CD1a antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product CD1a Primärantikörper
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- Applikationshinweise
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD1a antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store the CD1a antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Target
- CD1a
- Andere Bezeichnung
- CD1a (CD1a Produkte)
- Synonyme
- CD1 antikoerper, FCB6 antikoerper, HTA1 antikoerper, R4 antikoerper, T6 antikoerper, CD1A antikoerper, CD1a molecule antikoerper, CD1 antigen antikoerper, T-cell surface glycoprotein CD1a antikoerper, CD1A antikoerper, CD1.1 antikoerper, LOC100156095 antikoerper, LOC101111409 antikoerper
- Hintergrund
- At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
- Gen-ID
- 909
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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