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Dityrosine Antikörper

DT WB, EIA, IHC (p) Wirt: Maus Monoclonal 1C3 unconjugated
Produktnummer ABIN492669
  • Target Alle Dityrosine (DT) Produkte
    Dityrosine (DT)
    Wirt
    • 11
    Maus
    Klonalität
    • 11
    Monoklonal
    Konjugat
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Dityrosine Antikörper ist unkonjugiert
    Applikation
    • 11
    • 11
    • 10
    • 10
    • 10
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    Protein A Chromatography
    Immunogen
    3-(p-hydroxyphenyl) propionic acid dimer KLH-conjugated
    Klon
    1C3
    Isotyp
    IgG2a
  • Applikationshinweise
    ELISA (Ref.1,2)Western bLot (Ref.3,5)Immunohistochemistry on Paraffin Sections (Ref.4).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore in 200 μL aqua bidest to 0.1 mg/mL
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody at -20 °CAfter reconstitution, store as frozen aliquotsAvoid repeated freezing and thawingShelf life: One year from despatch.
    Haltbarkeit
    12 months
  • Li, Shi, Ding, Ran, Le: "Dietary oxidized tyrosine (O-Tyr) stimulates TGF-β1-induced extracellular matrix production via the JNK/p38 signaling pathway in rat kidneys." in: Amino acids, Vol. 49, Issue 2, pp. 241-260, (2018) (PubMed).

  • Target
    Dityrosine (DT)
    Andere Bezeichnung
    Dityrosine / DT (DT Produkte)
    Substanzklasse
    Dipeptide
    Hintergrund
    Tyrosine is one of the major targets of protein oxidation, and until today various tyrosine derivatives such as nitrotyrosine, dityrosine and halogenated tyrosine depending on the type of free radicals. DT is a tyrosine dimer derived from tyrosyl radicals which is formed by reactive oxygen species (ROS), metal-catalyzed oxidation, ultraviolet irradiation, and peroxidases. DT have been found in atherosclerotic lesions, and lipofuscin of pyramidal neurons of aged human brains. Dityrosine is one of the specific biomarkers for protein oxidation.
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