DC-SIGN/CD209 Antikörper (Extracellular Domain)

Produktnummer ABIN492511

Dieses Maus Monoklonal-Antikörper erkennt spezifisch DC-SIGN/CD209 in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DC-SIGN/CD209 Antikörper (Extracellular Domain) (ABIN492511)

Target: DC-SIGN/CD209 (CD209) (CD209)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: 8B6

Produktdetails anti-DC-SIGN/CD209 Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: Recognizes CD209 / DC-SIGN.

Produktmerkmale: Synonyms: DCSIGN1, DCSIGN, DC-SIGN1, CLEC4L, Dendritic Cell Marker, Dendritic cell-specificICAM-3-grabbing non-integrin 1, C-type lectin domain family 4 member L

Aufreinigung: Immunoaffinity Chromotography.

Immunogen: A recombinant His-tagged protein fragment corresponding to the extracellular region ofHuman DC-SIGN.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1-2 μg/mLImmunohistochemistry: 5-10 μg/mLPositive Controls: Human Uterus Tissue Lysate, Human Lymph Node Tissue Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Andere Bezeichnung: CD209 / DC-SIGN

Hintergrund: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes (1), where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN (2). ICAM-3 is the natural ligand for DC-SIGN (3). A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently (4-8). DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR (8). The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

Gen-ID: 30835

UniProt: Q9NNX6