DC-SIGN/CD209 Antikörper (Extracellular Domain)

Produktnummer ABIN492510

Produktdetails anti-DC-SIGN/CD209 Antikörper

Target: DC-SIGN/CD209 (CD209) (CD209)

Bindungsspezifität: Extracellular Domain

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: Recognizes CD209 / DC-SIGN.

Produktmerkmale: Synonyms: DCSIGN1, DCSIGN, DC-SIGN1, CLEC4L, Dendritic Cell Marker, Dendritic cell-specificICAM-3-grabbing non-integrin 1, C-type lectin domain family 4 member L

Aufreinigung: Immunoaffinity Chromotography.

Immunogen: A recombinant His-tagged protein fragment corresponding to the extracellular region ofHuman DC-SIGN.

Klon: 5D7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1-2 μg/mLImmunohistochemistry: 5-10 μg/mLPositive Controls: Human Uterus Tissue Lysate, Human Lymph Node Tissue Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Andere Bezeichnung: CD209 / DC-SIGN (CD209 Produkte)

Synonyme: CDSIGN antikoerper, CLEC4L antikoerper, DC-SIGN antikoerper, DC-SIGN1 antikoerper, cd209 antikoerper, CLEC4M antikoerper, si:ch211-224h1.3 antikoerper, CD209 antikoerper, CIRE antikoerper, Dcsign antikoerper, SIGN-R1 antikoerper, SIGNR5 antikoerper, Cd209 antikoerper, CD209 molecule antikoerper, CD209a antigen antikoerper, CD209 antigen-like protein D antikoerper, CD209c molecule antikoerper, CD209 antigen antikoerper, CD209 antikoerper, cd209 antikoerper, Cd209a antikoerper, LOC100529184 antikoerper, Cd209c antikoerper, LOC100460708 antikoerper, LOC105484282 antikoerper

Hintergrund: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes (1), where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN (2). ICAM-3 is the natural ligand for DC-SIGN (3). A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently (4-8). DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR (8). The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

Gen-ID: 30835

UniProt: Q9NNX6