Lectin Antikörper

Produktnummer ABIN492365

Produktdetails

Target: Lectin

Reaktivität: Mistletoe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Aufreinigung: Purified

Immunogen: Recombinant Mistletoe Lectin

Klon: 2G8-F7

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in aqua bidest to 1 mg/mL

Buffer: PBS, pH 7.4

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Antigendetails

Target: Lectin

Hintergrund: Mistletoe lectin I (ML-I) is a type II ribosome-inactivating protein, which inhibits the protein biosynthesis at the ribosomal level. ML-I is composed of a catalytically active A-chain with rRNA N-glycosidase activity and a B-chain with carbohydrate binding specificities. Using comparative solid-phase binding assays along with electrospray ionization tandem mass spectrometry, ML-I was shown to preferentially bind to terminally α2-6-sialylated neolacto series gangliosides from human granulocytes.Researchers across Europe (centres include Moscow, Berlin and London) have been investigating what specific properties of Viscum album could affect cancer cells. They have confirmed that some chemicals in European mistletoe can have anticancer properties. These properties are linked to various cytotoxic and immuno-modulatory compounds found in mistletoe, mainly the chemicals known as Viscotoxins and Mistletoe Lectins.