USP14 Antikörper

Produktnummer ABIN4915065

Dieses Anti-USP14-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von USP14 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für USP14 Antikörper (ABIN4915065)

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser USP14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 9C1

Produktdetails anti-USP14 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged USP14 protein was used to produced this monoclonal antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu USP14

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Andere Bezeichnung: USP14

Hintergrund:

Synonyms: TGT, Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14, USP14

Background: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

Gen-ID: 9097

UniProt: P54578