NOS1 Antikörper (pSer1417)

Produktnummer ABIN4912434

Dieses Anti-NOS1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NOS1 in WB, ELISA, ICC, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Human, Ratte und Xenopus laevis.

Kurzübersicht für NOS1 Antikörper (pSer1417) (ABIN4912434)

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Reaktivität: Human, Ratte, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NOS1 Antikörper

Bindungsspezifität: pSer1417

Kreuzreaktivität: Human, Ratte, Xenopus laevis

Homologie: Mouse,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human nNOS around the phosphorylation site of Ser1417

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NOS1

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Andere Bezeichnung: nNOS

Hintergrund:

Synonyms: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP9

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Gen-ID: 842

UniProt: P55211

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction