JUP Antikörper

Produktnummer ABIN4911274

Dieses Maus Monoklonal-Antikörper erkennt spezifisch JUP in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für JUP Antikörper (ABIN4911274)

Target: JUP (Junction Plakoglobin (JUP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser JUP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 6C1

Produktdetails anti-JUP Antikörper

Kreuzreaktivität: Human

Aufreinigung: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This JUP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 636-663 amino acids from human JUP .

Isotyp: IgG3

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu JUP

Target: JUP (Junction Plakoglobin (JUP))

Andere Bezeichnung: JUP

Hintergrund:

Synonyms: DP3, PDGB, PKGB, CTNNG, DPIII, ARVD12, Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3, JUP

Background: Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).

Gen-ID: 3728

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location